| Epinephrine bitartrate Basic information |
| Product Name: | Epinephrine bitartrate |
| Synonyms: | L-3,4-DIHYDROXY-ALPHA- [(METHYLAMINO)METHYL] BENZYL ALCOHOL BITARTRATE;L-ADRENALINE BITARTRATE;L-ADRENALINE D-HYDROGENTARTRATE;L-ADRENALINE (+)-BITARTRATE SALT;L-ADRENALINE HYDROGEN TARTRATE;L-EPINEPHRINE D-HYDROGENTARTRATE;L-(-)-EPINEPHRINE-(+)-BITARTRATE;L-EPINEPHRINE BITARTRATE |
| CAS: | 51-42-3 |
| MF: | C13H19NO9 |
| MW: | 333.29 |
| EINECS: | 200-097-1 |
| Product Categories: | BRONITIN;API |
| Mol File: | 51-42-3.mol |
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| Epinephrine bitartrate Chemical Properties |
| Melting point | ~155 °C (dec.) |
| refractive index | -16.5 ° (C=2, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble |
| form | solid |
| color | white |
| Merck | 13,3650 |
| Stability: | Stable. Incompatible with bases, oxidizing agents, iron, iron salts, copper, copper alloys. |
| InChI | InChI=1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10) |
| InChIKey | YLXIPWWIOISBDD-NDAAPVSOSA-N |
| SMILES | OC1=C(O)C=CC(C(CNC)O)=C1.OC(C(C(C(O)=O)O)O)=O |
| CAS DataBase Reference | 51-42-3(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | T+ |
| Risk Statements | 28-36/37/38 |
| Safety Statements | 26-28-36/37-45 |
| RIDADR | UN 2811 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | DO3500000 |
| F | 8-10-23 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29379000 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Epinephrine bitartrate Usage And Synthesis |
| Description | Epinephrine bitartrate is the bitartrate salt form of epinephrine, a direct-acting sympathomimetic amine with bronchodilator and vasoconstricting activity. Epinephrine bitartrate acts on both alpha and beta-adrenergic receptors. By stimulating alpha-adrenergic receptors locally, this agent causes vasoconstriction and reduces vascular blood flow. Administered in the conjunctiva, epinephrine bitartrate induces vasoconstriction and decreases the production of aqueous humor mediated through alpha-adrenergic receptors. This agent relaxes bronchial smooth muscle through its beta-stimulating actions and causes bronchodilation. |
| Chemical Properties | solid |
| Uses | Epinephrine bitartrate is an adrenergic agonist, bronchodilator, antiglaucoma agent. |
| Uses | vasodilator |
| Brand name | Bronitin (Wyeth); Medihaler-EPI (3MPharmaceuticals). |
| General Description | α,β-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP. |
| Biochem/physiol Actions | Primary Targetα,β-Adrenergic receptor agonist |